plasmart.org

SEQUENCE ME

A Plasmart Initiative

Preserve your family's genome.

Map every clotting factor. Own the data that could change everything.

White-glove whole-genome sequencing and archival for families affected by hereditary blood factor deficiencies.

A · T · G · C → I · II · V · VII · VIII · IX · X · XI · XII · XIII
Order Sequencing The Mission
Our Mission

Curing all human blood factor mutations — permanently, precisely, across generations.

By analyzing parental and child DNA, we seek to pioneer precise interventions that correct underlying mutations at their source — so children, grandchildren, and generations to come can live free from the burden of bleeding disorders.

The Blood Coagulation Cascade — intrinsic and extrinsic pathways converging on fibrin clot formation

The coagulation cascade: a complex network of proteins working in harmony. A single nucleotide change in any factor can cause a bleeding disorder.

Why Whole-Genome Sequencing

Consumer tests miss what matters.

Genotyping arrays check a few hundred thousand positions. 30x whole-genome sequencing reads all 3.2 billion base pairs — every coagulation factor gene, end to end.

GeneCondition30x WGSGenotyping
F8Hemophilia A186,5613
F9Hemophilia B33,7840
VWFvon Willebrand Disease179,4266
F5Factor V Deficiency71,1221
F7Factor VII Deficiency31,3300
F11Factor XI Deficiency55,1880
F13A1Factor XIII Deficiency66,9940

Variant counts per gene. Genotyping checks markers; sequencing reads the entire gene. Data from Sequencing.com.

Coagulation Factor Panel

Every factor. Every variant.

Hereditary deficiencies in any of the thirteen coagulation factors cause bleeding disorders. 30x whole-genome sequencing covers them all.

IFibrinogen
IIProthrombin
VProaccelerin
VIIProconvertin
VIIIAnti-hemophilic A
IXChristmas Factor
XStuart–Prower
XIPTA
XIIHageman
XIIIFibrin-Stabilizing

The full panel — from code to cure. Sequencing today gives families the data that future gene therapies will need.

Sample Report

What a coagulation report looks like.

Based on Sequencing.com's Healthcare Pro report format — the same structure used for clinical-grade genetic findings.

Coagulation Factor Analysis
Healthcare Pro DNA Report
ID: MR-1985-XXXX
⚠ Risk Detected
F8 — c.3780C>A (p.Tyr1260*)
Nonsense variant in Factor VIII gene associated with Hemophilia A. This stop-gain variant is predicted to result in a truncated, nonfunctional Factor VIII protein.
Recommendation: Confirm with clinical-grade testing. Referral to hematology for coagulation assessment.
⚑ Variant of Uncertain Significance
VWF — c.2561G>A (p.Arg854Gln)
Missense variant in von Willebrand Factor. Reported in individuals with Type 1 von Willebrand disease. Functional significance not fully established.
Recommendation: Clinical correlation with bleeding history. Consider vWF antigen and activity assays.
✓ No Pathogenic Variants
F9, F5, F7, F10, F11, F12, F13A1, F13B, F2, FGA, FGB, FGG
No pathogenic or likely pathogenic variants detected in the remaining coagulation factor genes.
This report is based on genomic analysis only and does not account for age, BMI, lifestyle, medications, or clinical history. Genetic findings should be interpreted by a qualified healthcare professional. Reanalysis recommended as scientific knowledge evolves.

Illustrative example. Actual reports are generated by Sequencing.com's Healthcare Pro app from your raw WGS data.

Process

Intake to delivery in 10–14 weeks.

We handle every step. You provide the saliva.

01

Intake & Consent

Submit family information. Privacy-first naming (initials + birth year).

02

Kit Coordination

We order 30x WGS kits from Sequencing.com and ship to your family.

03

Sample Collection

Saliva or cheek swab at home. Activate online, return prepaid.

04

Sequencing

30x whole-genome sequencing. 6–10 weeks. Status updates throughout.

05

Archive & Delivery

Organized, checksummed, packaged on encrypted media. Delivered to your door.

What You Receive

A complete genome archive per family member.

MR-1985/
  raw/
    MR-1985_R1.fastq.gz — raw reads
    MR-1985_R2.fastq.gz — raw reads
  aligned/
    MR-1985.sorted.bam — aligned
  variants/
    MR-1985.g.vcf.gz — variants
  reports/
    sequencing_report.pdf
  README.md
Investment

Transparent pricing. No subscriptions.

$399
per family member · 30x whole-genome sequencing via Sequencing.com
  • Complete FASTQ, BAM, and VCF download
  • Lifetime data storage on Sequencing.com
  • 15,000+ health condition reports
  • Organized archive on encrypted media
  • Family grouping documentation
  • White-glove concierge coordination

Already have whole-genome data? Bring-your-own-data archival starts at $50.

🔒 HIPAA 🔬 CAP ✓ CLIA 🛡 Privacy Forever
Begin

Ready to sequence your family?

Order your 30x whole-genome sequencing kit directly through our Sequencing.com partnership.

Order Through Sequencing.com

30x whole-genome sequencing with full FASTQ, BAM, and VCF download. Lifetime storage. 15,000+ condition reports included.

Order Your Kit →

You'll be directed to Sequencing.com to complete your order. Sequence Me provides concierge coordination and archive delivery for families who want white-glove support.

Want concierge coordination for your whole family?

✉ Contact Sequence Me
Privacy & Scope

Your data. Your rules.

Privacy-first naming. Encrypted delivery. Your files go to you and nowhere else.

Not a medical service. Sequence Me is a nonclinical genome data preservation and concierge service. We do not provide medical advice, diagnosis, treatment, or genetic counseling. Sequencing is performed by Sequencing.com. Always consult qualified medical professionals for health decisions.
Questions

Frequently asked

How is this different from 23andMe?
23andMe uses a genotyping array — less than 0.1% of your genome. Sequence Me uses 30x whole-genome sequencing: all 3.2 billion base pairs. You receive raw data files (FASTQ, BAM, VCF), not just a report.
Do I need a doctor's order?
No. Sequence Me is a nonclinical service. You order kits directly through Sequencing.com. No physician involvement, no insurance billing, no medical record.
How long does it take?
10–14 weeks total. Kit shipping: ~1 week. Sequencing: 6–10 weeks. Archive preparation: 1–2 weeks.
Can I bring data I already have?
Yes. If you have 30x whole-genome data from Nebula, Dante Labs, or another provider, we can organize and archive it starting at $50.
Is my data shared with anyone?
No. Your genomic data is never sold, shared, or used for research. Sequencing.com provides lifetime storage. Your encrypted archive is delivered only to you.